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Vernon Chinchilli

职称: Professor

所属学校:Pennsylvania State University-Main Campus

所属院系:Clinical and Translational Science Institute

所属专业:Civil Engineering, General

联系方式: 7175314262

简介

Distinguished Professor and Chair of Public Health Sciences

职业经历

Vernon M. Chinchilli, PhD, is Distinguished Professor and Chair in the Department of Public Health Sciences at the Penn State Hershey College of Medicine. His prior professional experience includes two years as a post-doctoral fellow in mathematical statistics at the U.S. Food and Drug Administration and 11 years as Assistant Professor through Professor in the Department of Biostatistics at the Medical College of Virginia of Virginia Commonwealth University. He joined the Penn State Hershey College of Medicine as Professor in 1992. Dr. Chinchilli is Principal Investigator for the Data Coordination and Analyses Center (DCAC) of the Community and Child Health Network (CCHN), which is funded by the Eunice Kennedy Shriver National Institute of Child Health and Human Development for the period 2006-2012. The overall goal of the CCHN is to gain new insights into the reasons for the disparities in maternal health and child development. The goals of the first study originating from the Network are (1) to examine the factors associated with maternal allostatic load (a possible factor in poor pregnancy outcomes), and (2) to evaluate the usefulness of community-partnered participatory research for conducting research on health disparities. It is a multi-site, prospective cohort study of the influences of stress and resilience on maternal allostatic load and birth outcomes. A cohort in excess of 2,400 families has been recruited at delivery of the index child, such that at least 2,400 of the mothers complete the one-month interview. There has been oversampling among African American and Latina women, as well as women with preterm birth. Dr. Chinchilli has developed a statistical analysis plan for the CCHN study that consists of a canonical correlational analysis within the context of a multi-level statistical model. Dr. Chinchilli has been Principal Investigator for the Data Coordinating Center (DCC) of the Asthma Clinical Research Network (ACRN) since its inception in 1993. The ACRN is funded by the National Heart, Lung, and Blood Institute (NHLBI). The ACRN exhausted its funding in 2011, and it completed 15 clinical trials and 40 peer-reviewed publications. Dr. Chinchilli developed a new clinical trial design, called a matched crossover design, which was invoked for three of the 15 ACRN clinical trials. In the matched crossover design, participants are matched according to pre-specified matching criteria and then the matched set is randomized to a crossover sequence of treatments. The advantage of the matched crossover design is that it can provide more precision than an unmatched design, which translates into a smaller sample size. Dr. Chinchilli also has been Principal Investigator of the DCC for the Childhood Asthma Research and Education (CARE) Network since its inception in 1999 until 2007, and now functions as a Co-Investigator in the CARE Network. The CARE Network also is funded by the NHLBI. When the CARE Network exhausts its funding it 2012, it will have completed 8 clinical trials and currently 20 peer-reviewed publications have resulted from these clinical trials.

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