In collaboration with other laboratories, we seek to understand the microbial roles in several pathogen or disease associated processes. To address these topics, we employ ecological approaches utilizing a wide range of methods including high throughput sequencing, various “omics” methods, quantitative PCR, standard in vitro culture techniques as well as algorithmic and statistical analyses. In the agricultural arena, our research goals include extending our understanding of microorganisms that suppress plant pathogens. Previously, we identified a fungus (Dactylella oviparasitica)that suppresses a plant-parasitic nematode (Heterodera schachtii). Current projects include adding the population levels of this fungus to cropping decision models, which we anticipate will lead to higher crop yields and profitability for the growers. We are also developing new microbe-based strategies to control Huanglongbing, which is a bacterial disease that is dramatically impacting citrus production worldwide. Other research projects include identifying microorganisms involved in various human health and disease processes. Current projects include examining the role of intestinal bacteria in (i) inflammatory bowel disease (IBD), (ii) several types of cancer and, (iii) obesity and diabetes.