Research in the Holman lab generally lies at the intersection of organic, organometallic, and solid-state chemistry. Broadly, we are interested in molecular recognition and supramolecular chemistry ― the organization of molecules into multi-component entities through non-covalent forces. With respect to solution phase chemistry, our interests lead us to the design of molecules capable of selectively binding and/or sensing appropriate substrates, those capable of spontaneously organizing into interesting and complex structures, or those that might influence the organization of other molecules, perhaps for purposes of reaction (e.g., supramolecular organocatalysis). Applied to the solid-state, we use supramolecular principals to attempt to empirically design crystalline structure (e.g., crystal engineering), thereby being able to impart selected properties to materials. Research projects are inherently multidisciplinary, allowing students to develop expertise in synthetic organic and/or organometallic chemistry, physical organic chemistry, solid-state organic chemistry, powder and single crystal X-ray diffraction, various spectroscopic techniques (NMR, neutron scattering), thermal analysis, etc. Current projects involve: