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职称:Distinguished Professor
所属学校:University of California-Los Angeles
所属院系:Biochemistry
所属专业:Biochemistry
联系方式:(310) 825-8754
Professor Clarke received his B.A. degree from Pomona College in 1970 and his Ph.D. degree from Harvard University in 1976. After a two-year postdoctoral appointment as a Miller Fellow at the University of California at Berkeley, he joined the UCLA faculty in 1978.
Steven Clarke has been on the faculty of the UCLA Department of Chemistry and Biochemistry since 1978. He is currently a Professor of Biochemistry and Director of the UCLA Molecular Biology Institute. He was born in Los Angeles and attended public schools in Altadena and Pasadena, California. He did his undergraduate work at Pomona College in Claremont, majoring in Chemistry and Zoology. During this time, he did undergraduate research at the UCLA Brain Research Institute with Dr. James E. Skinner and Professor Donald Lindsley on neural mechanisms of attention. He was also an NIH fellow in the laboratory of Dr. Peter Mitchell at Glynn Research Laboratories in Bodmin, England studying mitochondrial amino acid transport. He obtained his PhD in Biochemistry and Molecular Biology at Harvard University working as an NSF Fellow with Professor Guido Guidotti on membrane protein-detergent interactions and the identification of the major rat liver mitochondrial polypeptides as enzymes of the urea cycle. He returned to California to do postdoctoral work as a Miller Fellow at the University of California, Berkeley, with Professor Dan Koshland, identifying membrane receptors for bacterial chemotaxis. His research at UCLA has focused on roles of novel protein methyltransferases in aging and biological regulation highlighted by discoveries of the protein L-isoaspartyl repair methyltransferase, the isoprenylcysteine protein methyltransferase, and the protein phosphatase 2A methyltransferase. He has been a visiting scholar at Princeton University (1986-87) and at the University of Washington (2004-2005). Professor Steven Clarke's 2009 UCLA Faculty Research Lecture on Nov. 3rd "Aging & Rejuvenation: Chemistry and Biology at Work" UCTV, Webcast, YouTube Professor Clarke accepts graduate students through the Biochemistry, Molecular and Structural Biology (BMSB) Graduate Program and the UCLA ACCESS Ph.D. Program.