简介

Our research is focused on the molecular mechanisms involved in the colonization of surfaces by microorganisms. We are particularly interested in a group of enzymes, the glucosyltransferases, formed by oral streptococci, and which form glucan from sucrose. These enzymes have distinct properties on surfaces compared with those observed when the enzymes are in solution. For example, glucan with a distinct structure may be formed on a surface compared with the product formed by the same enzyme in solution. Thus highly specific binding sites for bacteria may be formed on a surface. DSc | Dentistry, All Other | Ireland-National U of Ireland 1974 PhD | Dentistry, All Other | UK-U London Fac Med 1965 DMSc | Dentistry, All Other | Univ Rochester Sch Med/Dent 1959