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职称:professor
所属学校:University of California-Los Angeles
所属院系:Chemical Engineering
所属专业:Chemical Engineering
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The primary goal of Theme 1 is to develop property-activity relationships between fundamental physical/chemical properties of nanoparticles and biological responses, and from these relationships to develop predictive models. In a highly interactive feedback process, nanoparticles with designed physical and chemical properties are synthesized, characterized, and studied in Theme 2 using high content or high throughput methods to measure the responses of cells and organisms. Evaluation of the responses leads to further synthesis of designed materials and further testing until the predictions of a model are validated (or rejected). The successful models are shared with investigators in Themes 3-5 for incorporation in studies of fate and transport in the environment and of terrestrial and aqueous ecosystems.
The primary goal of Theme 1 is to develop property-activity relationships between fundamental physical/chemical properties of nanoparticles and biological responses, and from these relationships to develop predictive models. In a highly interactive feedback process, nanoparticles with designed physical and chemical properties are synthesized, characterized, and studied in Theme 2 using high content or high throughput methods to measure the responses of cells and organisms. Evaluation of the responses leads to further synthesis of designed materials and further testing until the predictions of a model are validated (or rejected). The successful models are shared with investigators in Themes 3-5 for incorporation in studies of fate and transport in the environment and of terrestrial and aqueous ecosystems.
