简介

I am an evolutionary ecologist with strong interests in the processes that drive heterogeneity in hosts, parasites, and diseases. I'm particularly keen to understand the role of immune systems in brokering host-parasite interactions, generating substantial self-harm (or immunopathology), and altering transmission dynamics of parasites. Recent projects in the Graham Group have focused on the following questions: Why do sheep vary so much in antibody responsiveness? What are the consequences of immunopathology for transmission of malaria parasites? Which cytokines primarily drive a cytokine storm? What are the relative roles of resource limitation and immunological killing in within-host control of parasite populations? Why do adaptive immune responses cross-react?