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职称:Robert P. Pinkas Family Professor of Bioengineering
所属学校:Harvard University
所属院系:Bioengineering
所属专业:Bioengineering and Biomedical Engineering
联系方式:(617) 384-9624
The basic question that drives Mooney's research is: how do mammalian cells receive information from the materials in their environment. By utilizing the tools of cell and molecular biology, he studies the mechanisms by which chemical (for example, specific cell adhesion molecules) or mechanical signals (for example, cyclic strain) are sensed by cells and alter their proliferation and specialization to either promote tissue growth or destruction. Mooney uses the results from these studies to design and synthesize new biomaterials that regulate the gene expression of interacting cells for a variety of tissue engineering and drug delivery projects. Current projects focus on therapeutic angiogenesis, regeneration of musculoskeletal tissues, and cancer therapies.
The basic question that drives Mooney's research is: how do mammalian cells receive information from the materials in their environment. By utilizing the tools of cell and molecular biology, he studies the mechanisms by which chemical (for example, specific cell adhesion molecules) or mechanical signals (for example, cyclic strain) are sensed by cells and alter their proliferation and specialization to either promote tissue growth or destruction. Mooney uses the results from these studies to design and synthesize new biomaterials that regulate the gene expression of interacting cells for a variety of tissue engineering and drug delivery projects. Current projects focus on therapeutic angiogenesis, regeneration of musculoskeletal tissues, and cancer therapies.