简介

My laboratory has initiated a functional genomics program here at AECOM. Usually we associate the study of gene expression and function with one or at most a few genes. We are now capable of simultaneously and quantitatively studying thousands of genes at once using DNA microarray chip technology. To do this we have built a robot to deposit thousands of PCR products of cDNA clones on small glass slides. Current generation chips contain 28,000 genes. We have always been interested in embryonic gene expression, lineage commitment and developmental biology. We have been using microarray technology to study cardiac myocyte differentiation from stem cell models in cell culture (see publications below).