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The accrued knowledge about the scientific basis of neurological disease is transforming the clinical practice of neurology in unprecedented ways. Identification of the genetic causes or cellular mechanisms underlying Huntington’s disease, the inherited ataxias, Alzheimer’s disease, multiple sclerosis, stroke, Parkinson’s disease, and neuromuscular disorders have already led to new approaches to diagnosis and treatment. The Department of Neurology at Boston University School of Medicine is committed to the integration of new understanding of the neurobiology of disease into the clinical practice of neurology and the training of neurological physicians, in order to provide better health care for patients with neurological diseases. The primary missions of the Department of Neurology are: to provide excellent, state-of-the-art medical care to patients with neurological diseases; to contribute to the advancement of new knowledge through basic and clinical neuroscience research; and to train physicians who will possess the skills to deliver comprehensive neurological care and advance new knowledge in the clinical neurosciences. These missions are executed at Boston Medical Center and the VA Boston Healthcare System. These institutions have been the source of significant contributions to the history of American neurology and, today, are busy clinical services that provide care to patients with a broad range of acute and chronic neurological diseases. This tradition of scientific investigation, training, and patient care continues within active programs in behavioral neurology, memory disorders, neuroepidemiology, movement disorders, sleep medicine, neurogenetics, stroke, neurocritical care, and epilepsy. See the Neurology website for more information.