Saleem researches statistical signal processing and communications. His study of through-wall imaging radar aims to provide new methods for imaging building interiors based on optimum use of array elements and co-array locations and frequency assignments. Saleem is also developing wireless communication systems using nonlinear blind signal separation and equalization to mitigate the effects of multi-path and other channel impairments. Additionally, Saleem works with bio-medical applications of signal processing, such as seizure monitoring and detection using EEG signals, and with nonlinear and adaptive signal and image processing methods.