Dr. Berry’s major interests lie in two areas: cardiovascular biomechanics and tissue engineering. His research has focused largely on modeling the fluid and solid mechanical effects of metallic stents placed into normal and diseased arteries. His group has published more than 10 papers on this subject and received 4 patents for metallic stent designs as well created a startup company around 2 of the patents. In addition to theoretical and experimental in vitro modeling of stents, he has designed and conducted several pre-clinical studies in swine and primate peripheral arteries, the outcome of which have demonstrated that the stent structure has a profound influence on the arterial response. It is from this base of knowledge and experience that his research has led to the concept of perfused, cell-seeded, prevascularized scaffolds for the purpose of overcoming oxygen diffusion limitations in engineered tissues. Dr. Berry has developed a technique for prevascularizing scaffold materials with 250 micron channels and shown that these channels also support a layer of endothelial cells under pulsatile flow conditions. This work is aimed at resolving some important limitations that currently exist 2D in vitro and in vivo animal studies that are current paradigm in anti-cancer drug development.