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职称:Professor
所属学校:University of Alabama at Birmingham
所属院系:Bioengineering
所属专业:Bioengineering and Biomedical Engineering
联系方式:(205) 975-2101
ACADEMIC BACKGROUND PhD, Biomedical Engineering, Duke University, 1988 MS, Biomedical Engineering, Duke University, 1985 BS, Biomedical Engineering, Duke University, 1983 TEACHING BME 461 - Bioelectric Phenomena BME 423 - Living Systems Analysis RESEARCH My research interests have focused on computational modeling and cardiac mapping strategies to improve understanding of arrhythmia development. Over the course of the past 5 years, those interests have shifted from analyses of electrical interactions between the specialized conduction system and the overlying ventricular myocardium to analyses of electrical source-load interactions that promote conduction failure at the cellular level. In making this shift, I have worked with a number of different investigators to design and test microelectrical mechanical systems (MEMS) arrays containing very small and closely spaced electrodes positioned in the interstitium. The use of MEMS arrays has the potential to provide fundamentally new descriptions of arrhythmia substrate development in heart and tissue preparations at a resolution more commonly associated with single cell electrophysiologic studies. Integration of detailed modeling is advantageous in this regard, as it provides a formal way in which recordings made with the MEMS systems can be interpreted. Microimpedance measurements are a specific focus. RECENT PUBLICATIONS (2008-2010) Pollard AE, Ellis CD, Smith WM: Fabrication and testing of linear electrode arrays suitable for stimulation and recording within cardiac tissue space constants. IEEE Trans. Biomed. Eng., 55:1408-1414, 2008
Ideker RE, Rogers JM, Pollard AE: Progress in modeling cardiac electrical activity. A long way from spherical cows. Heart Rhythm, 5:1045-6, 2008 Sims JA, Pollard AE, White PS, Knisley SB: Stimulatory current at the edge of an inactive conductor in an electric field. Role of nonlinear interfacial current-voltage relationship. IEEE Trans. Biomed. Eng, 2010 Feb;57(2):442-9. Epub 2009 Jul 14 Pollard AE, Barr RC: A biophysical model for cardiac microimpedance measurements. Am. J. Physiol. Heart Circ. Physiol., 2010;298 H1699-H1709 RESEARCH FUNDING (2008-2010) Novel Methods for Cardiac Microimpedance Measurements. National Institutes of Health, 2009-2014; NIH Model and Experimental Studies of Cardiac Conduction Block Using Microscopic Electrical Mapping. 2008-2011; NSF