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职称:Professor, Biomedical Engineering Professor, Molecular and Integrative Physiology
所属学校:University of Michigan-Ann Arbor
所属院系:Biomedical Engineering
所属专业:Bioengineering and Biomedical Engineering
联系方式: (734) 936-2147
Research in Dr. Brooks' laboratory focuses on age-associated changes in skeletal muscle and tendon. We are particularly interested in the role of injury in the loss of muscle mass and strength with aging. In vivo and in vitro approaches are combined to determine the mechanisms underlying changes with aging in susceptibility to injury, muscle regenerative capacity, and the ability to induce protective adaptations. In addition, high resolution optical techniques are coupled with measures of protein expression, collagen content, and amino acid cross-linking to clarify the basis for regional mechanical properties of tendons and to define the changes in the structure and composition of the extracellular matrix with aging.
Research in Dr. Brooks' laboratory focuses on age-associated changes in skeletal muscle and tendon. We are particularly interested in the role of injury in the loss of muscle mass and strength with aging. In vivo and in vitro approaches are combined to determine the mechanisms underlying changes with aging in susceptibility to injury, muscle regenerative capacity, and the ability to induce protective adaptations. In addition, high resolution optical techniques are coupled with measures of protein expression, collagen content, and amino acid cross-linking to clarify the basis for regional mechanical properties of tendons and to define the changes in the structure and composition of the extracellular matrix with aging.
