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职称:Associate Professor of Human Genetics Associate Professor of Neurology
所属学校:University of Michigan-Ann Arbor
所属院系:human genetic
所属专业:Human/Medical Genetics
联系方式:734-647-4058
Our overarching objective is to understand the development and diseases of the peripheral nervous system, the latter including Charcot-Marie-Tooth (CMT) disease. CMT is a relatively common peripheral neuropathy that mainly affects motor and sensory function in the extremities (feet, lower legs, and hands). The major types of CMT are those that affect myelinating Schwann cells (CMT1) and those that affect peripheral nerve axons (CMT2). Our efforts are divided into two major areas: (1) Determining the role of tRNA charging enzymes in peripheral neuropathy; and (2) Characterizing genes important for Schwann cell development and function. Please visit http://hg.med.umich.edu/labs/antonellis/Antonellis_Laboratory/Projects.html for a description of the projects in our laboratory
Our overarching objective is to understand the development and diseases of the peripheral nervous system, the latter including Charcot-Marie-Tooth (CMT) disease. CMT is a relatively common peripheral neuropathy that mainly affects motor and sensory function in the extremities (feet, lower legs, and hands). The major types of CMT are those that affect myelinating Schwann cells (CMT1) and those that affect peripheral nerve axons (CMT2). Our efforts are divided into two major areas: (1) Determining the role of tRNA charging enzymes in peripheral neuropathy; and (2) Characterizing genes important for Schwann cell development and function. Please visit http://hg.med.umich.edu/labs/antonellis/Antonellis_Laboratory/Projects.html for a description of the projects in our laboratory
